Formulation and Evaluation of Losartan Potassium Osmotic Controlled Matrix Tablets
نویسندگان
چکیده
منابع مشابه
Mouth Dissolving Tablets of Losartan Potassium: Formulation and Evaluation
Losartan potassium is an angiotention receptor antagonist, used in the management of hypertension. The objective of the proposed research work is to prepare and evaluate the mouth dissolving/disintegrating tablets (MDTs) of losartan Potassium, which avoid the first-pass metabolism, improved the dissolution rate and enhance the bioavailability. Mouth dissolving tablets (MDTs) were prepared by di...
متن کاملFormulation and Evaluation of Diclofenac Potassium Matrix Tablets
The objective of the study was to develop HPMC matrix tablets for oral controlled/ sustained release of water soluble Diclofenac Potassium. Sustained release matrix tablets containing 100 mg of Diclofenac Potassium were developed using different drug polymer ratio of HPMC. Tablets were prepared by direct compression. Compressed tablets were evaluated for uniformity of weight, content of active ...
متن کاملFormulation and Evaluation of Sustained Release Matrix Tablets of Glipizide
The purpose of this study was to develop a new monolithic matrix tablet to completely deliver glipizide in a zero order manner over a sustained period. Two approaches were examined using drug in a formulation that contain polymer like hydroxylpropyl methyl-cellulose K 100 (HPMCK) and Eudragit L 100. The granules were prepared by wet granulation method and thereby formulated as F-1, F-2. F...
متن کاملFormulation and in Vitro Evaluation of Losartan Potassium Mucoadhesive Buccal Tablets
Objective: The Losartan potassium mucoadhesive buccal tablet were prepared using mucoadhesive polymers such as Carbopol 940P, pectin, sodium CMC, Sodium alginate, HPMC K4M, HPMC K15M and HPMC K100M in alone and in combination as release retarding agent to prolong the drug release and to avoid first pass metabolism. Methods: The mucoadhesive buccal tablets were prepared by direct compression met...
متن کاملDesign and Evaluation of Losartan Potassium Matrix Tablets with Natural and Synthetic Polymers
The objective of the study was to formulate controlled release matrix tablets of losartan Potassium by using a combination of hydrophilic synthetic polymer like poly (ethylene oxides) and natural gums like xanthan gum, karaya gum and guar gum. A combination of synthetic hydrophobic polymers like methacrylates with synthetic hydrophilic polymer like poly (ethylene oxide) was also used in the pre...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Indian Journal of Pharmaceutical Education and Research
سال: 2014
ISSN: 0019-5464
DOI: 10.5530/ijper.48.4s.3